Here's my EnrollmentService.log:
[3, PID:7248][05/02/2013 16:13:45] :EnrollmentService application start ...
[7, PID:7248][05/02/2013 16:13:47] :WindowsIdentity is created for domain: [Domain] user: [user]
[7, PID:7248][05/02/2013 16:13:47] :validated user credentials
[7, PID:7248][05/02/2013 16:13:47] :Handling RequestSecurityToken
[7, PID:7248][05/02/2013 16:13:47] :claim identity name: [Domain\User]
[7, PID:7248][05/02/2013 16:13:47] :ConfigManager: RefreshCache: Creating Enrollment Profile 16777217
[7, PID:7248][05/02/2013 16:13:47] :EnrollmentServiceProfile: GetDBCAs retrieved Template information:
[7, PID:7248][05/02/2013 16:13:47] :Template: CM12ClientCert
[7, PID:7248][05/02/2013 16:13:47] :CA: System.Collections.Generic.List`1[system.String]
[7, PID:7248][05/02/2013 16:13:47] :The CA [CA] is in forest [Domain]
[7, PID:7248][05/02/2013 16:13:47] :Impersonating caller: [user]
[7, PID:7248][05/02/2013 16:13:47] :Revert back to self: NT AUTHORITY\NETWORK SERVICE
[7, PID:7248][05/02/2013 16:13:47] :ConfigManager: Sending CA Success Status - ENROLLSRVMSG_CA_SUCCESS
[7, PID:7248][05/02/2013 16:13:47] :ConfigManager: CA Chains count: 1
[7, PID:7248][05/02/2013 16:13:47] :ConfigManager: Subject name: [...]
[7, PID:7248][05/02/2013 16:13:47] :ConfigManager: Issuer Name: [...]
[7, PID:7248][05/02/2013 16:13:47] :ConfigManager: CA Chains 1 thumprint: [...]
[7, PID:7248][05/02/2013 16:13:47] :ConfigManager: Got root CA hash: [...]
[7, PID:7248][05/02/2013 16:13:47] :Impersonating caller: [Domain\User]
[7, PID:7248][05/02/2013 16:13:48] :Revert back to self: NT AUTHORITY\NETWORK SERVICE
[7, PID:7248][05/02/2013 16:13:48] :EnrollmentRequestController: entering State: Start
[7, PID:7248][05/02/2013 16:13:48] :EnrollmentRequestController: exiting state: Start, Result: Succeed
[7, PID:7248][05/02/2013 16:13:48] :EnrollmentRequestController: entering State: AuthenticationApproved
[7, PID:7248][05/02/2013 16:13:48] :EnrollmentRequestController: exiting state: AuthenticationApproved, Result: Failover
[7, PID:7248][05/02/2013 16:13:48] :EnrollmentRequestController: entering State: CertNotInADAccount
[7, PID:7248][05/02/2013 16:13:48] :Impersonating caller: [Domain\User]
[7, PID:7248][05/02/2013 16:13:48] :Revert back to self: NT AUTHORITY\NETWORK SERVICE
[7, PID:7248][05/02/2013 16:13:48] :CALayer: Sending CA failure status - ENROLLSRVMSG_CA_FAILURE
[7, PID:7248][05/02/2013 16:13:48] :CALayer: SubmitRequest CA: [CA] Errormessage: Denied by Policy Module 2 ErrorCode: 2
[7, PID:7248][05/02/2013 16:13:48] :Only one CA is specified in profile. Failed to enroll with the specified CA: [CA]
[7, PID:7248][05/02/2013 16:13:48] :EnrollmentRequestController: Enrollment exception Error Code:FailedToIssueCert Message: Submitting cert request and issuing cert failed
[7, PID:7248][05/02/2013 16:13:48] :Microsoft.ConfigurationManagement.Enrollment.EnrollmentServerException: Submitting cert request and issuing cert failed
at Microsoft.ConfigurationManagement.Enrollment.CALayer.SubmitRequest(EnrollmentRequestState enrollRequest)
at Microsoft.ConfigurationManagement.Enrollment.EnrollmentRequestController.Execute()
at Microsoft.ConfigurationManagement.Enrollment.RequestHandler.ProcessRequestSecurityToken(RequestSecurityTokenType request, WindowsIdentity caller, ActionEnum action)
at Microsoft.ConfigurationManagement.Enrollment.RequestHandler.EnrollDevice(Message messageRequest)
at Microsoft.ConfigurationManagement.Enrollment.DeviceEnrollmentService.RequestSecurityToken(Message messageRequest)
[7, PID:7248][05/02/2013 16:13:48] :FaultCode is: CertificateRequest and reason is: Failed certificate operations FailedToIssueCert